Big Ten Rivalry: Indiana Hosts USC in Week 11

No. 9 Indiana hosts No. 18 USC on Saturday at 3:30 p.m. ET, capping a busy Week 11 college football schedule. The Hoosiers, who hold the national championship, are seeking a signature victory after a light non-conference slate. Their only loss this season came against Ohio State. USC arrives well rested following an emphatic win over the Buckeyes and a subsequent bye week.

Betting lines favor Indiana by 7.5 points, with the total set at 49.5. The matchup pits a team looking to cement its status against a visiting squad that has had ample time to prepare under a less demanding schedule. This contest is the headline event of the weekend, drawing attention from fans of both the Big Ten and the national narrative.

The schedule opens Friday night with Florida State visiting Pittsburgh at 7 p.m. ET. The Seminoles fired head coach Mike Norvell after a 36-24 loss to Clemson and subsequently beat Boston College 31-24 under interim coach Rick Stockstill. Florida State currently stands at 4-5 and requires two more wins to reach bowl eligibility. Pittsburgh, at 6-3, is already eligible after snapping a three-game losing streak with a 34-11 victory over Georgia Tech.

Pittsburgh holds a 3.5-point home advantage, and the over/under for that contest is 54.5. On the same evening, No. 4 UCLA hosts Illinois at 9 p.m. ET. UCLA is one of two unbeaten teams in the FBS, standing at 9-0. Backup quarterback Ty Dieffenbach holds a higher passer rating of 142.9 compared to injured starter Nico Iamaleava’s 138.1. Illinois has won four straight games and remains in the Big Ten title hunt with a 4-2 league record. UCLA is favored by 10 points with a total of 46.5.

Saturday’s noon window features No. 7 Miami hosting Duke. Miami is adjusting to the absence of star receiver Malachi Toney due to an ankle injury after suffering its first loss of the season. Duke, the reigning ACC champion, has outscored opponents 88-5 over the last two weeks. Coach Manny Diaz faces his former team, with Miami favored by 13.5 points and the total set at 54.5. In Dallas, No. 13 Wake Forest visits SMU in another ACC title race, with Wake Forest holding a 1.5-point road advantage over the Mustangs.

No. 20 Ohio State hosts Northwestern at noon, having lost two straight games to USC and Oregon since losing quarterback Julian Sayin. The Buckeyes surrendered 71 points in those defeats and are favored by 12.5 points over Northwestern, a team that has not won at Ohio Stadium since 1971. Later that day, No. 8 Tennessee visits Texas A&M at 3 p.m. ET, with the Volunteers favored by 2.5 points despite falling to 4-5 this season.

In the evening, No. 11 Kentucky hosts Florida at 6:15 p.m. ET, with Kentucky favored by 3.5 points. The Wildcats remain in the playoff picture despite a recent loss to Tennessee. In the 7:30 p.m. ET slot, No. 6 Texas visits No. 21 LSU, where the Tigers are favored by 3.5 points despite Texas winning their previous game. No. 2 Utah puts its 15-game winning streak on the line at No. 23 Arizona, holding a 2.5-point road advantage. The night concludes with No. 25 Oklahoma State hosting No. 12 Texas Tech at 9:30 p.m. ET, with Oklahoma State favored by 3.5 points and the total set at 72.5.